The Neuromuscular Clinical Laboratory provides Antibody testing Antibodies tested Test request form Neuromuscular pathology (Muscle & Nerve biopsies). We evaluate more than 600 muscle & 100 …

See Neuromuscular Syndromes Go to Differential Diagnosis of Neuropathies Return to Neuromuscular Home Page or newly revised Other revisions 2/14/2024

General: The neuromuscular evaluation Begins with: Evaluation & description of patterns of disease process Gleaned from: History & physical examination Unusual patterns Especially important …

Paraneoplastic Lower Motor Neuron Syndrome 8, 25 Epidemiology: Single patient, 72 year old female Onset: 4 months before diagnosis of tumor Clinical Weakness Asymmetric at onset Arms & Legs …

GENERAL INDICATIONS FOR MUSCLE BIOPSIES Presence of some evidence of muscle disease Weakness Muscle symptoms: Discomfort; Cramps; Fatigue with activity (r/o myasthenia) Elevated …

Neuromuscular Muscle stiffness Myotonia: Onset after birth Face: Fixed expression, Pursed lips, Small mouth Thighs Waddling gait Crouched stance Treatment: Carbamazepine Muscle hypertrophy: …

I. Clinical Indications for Measurement of anti-MAG antibodies Diagnostic work-ups of adult onset, symmetric polyneuropathies, especially with: Clinical features Predominantly distal numbness ± …

NEUROMUSCULAR CLINICAL LABORATORY: Antibody Information ... To obtain antibody testing: · Draw blood in a red top tube · Send: 2 to 3 ml of serum · Send with requisition, at room temp …

Motor point muscle biopsies Count AChRs at neuromuscular junctions Evaluate neuromuscular transmission by in vitro electrophysiologic methods Immunocytochemical staining of muscle …

Variation in fiber size Occasional necrotic fiber EM Elliptical bodies between muscle fibers Simplified neuromuscular junctions Variation in fiber size