Mar 6, 2025 · MASLD is estimated to affect more than one-third of adults worldwide. MASLD is closely associated with insulin resistance, obesity, gut microbial dysbiosis and genetic risk …

Jun 30, 2023 · With its increasing prevalence rate, MASLD is becoming the most common indication for liver transplantation and the main underlying aetiology for the development of …

Oct 2, 2024 · In the past 20 years, the prevalence of MASLD has been rising rapidly, along with the contribution of MASLD as a major cause of cirrhosis and hepatocellular carcinoma (HCC).

Feb 21, 2024 · Non-alcoholic liver disease (NAFLD) is now metabolic dysfunction-associated steatotic liver disease (MASLD), emphasizing the key metabolic factors of obesity, insulin …

Aug 5, 2025 · MASLD and MASH are not confined to liver pathology but represent systemic metabolic disorders with profound implications across multiple organ systems.

Jan 10, 2025 · The new names for MASLD and MASH, respectively, stand for metabolic dysfunction-associated steatotic liver disease and metabolic dysfunction-associated …

Jun 10, 2025 · In this review, we describe the emerging data regarding the immunological mechanisms of MASLD (Fig. 1) and summarize data regarding new concepts related to …

Dec 9, 2024 · In the present study, using unsupervised hard clustering, we identified two distinct endotypes of at-risk MASLD, namely, cardiometabolic MASLD and liver-specific MASLD.

This publication is important because it provides a standardized clinical pathway for MASLD assessment and management, which will improve the identification and care of affected …

Feb 28, 2025 · Indeed, there should be a spotlight on MASLD: the condition currently affects around 30% of the global population, and a strong public health response is needed to …