“A good 20 years ago, we fundamentally broke the diffraction resolution limit of fluorescence microscopy with STED. Until then, that was considered impossible,” says Hell. “Back then we dreamed: With ...
Stimulated emission depletion (STED) microscopy is one of the family of super-resolution techniques developed to allow imaging beyond the normal diffraction limit of optical microscopy. The principle ...
Although fiber-optical two-photon endoscopy has been recognized as a potential high-resolution diagnostic and therapeutic procedure in vivo, its resolution is limited by the optical diffraction nature ...
Every now and again, I look at the work of other scientists and feel envious. Why haven't I managed to do something that exciting? Some people will respond by trying to find a new angle on the the ...
New microscopy method: MINSTED resolves fluorescent molecules with resolution at the nanometer scale
Scientists working with Stefan Hell at the Max Planck Institute (MPI) for Biophysical Chemistry in Göttingen and the Heidelberg-based MPI for Medical Research have developed another light microscopy ...
Researchers achieved nanometer-scale resolution without requiring a dark state, expanding super-resolution imaging to non-fluorescent molecules and non-optical waves. The findings published in Nature ...
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