Cell division is essential to the propagation of life. During cell division, mitotic spindles segregate duplicated chromosomes with high fidelity. Spindle structure depends on the proper polar ...
Robert Blackwell, Christopher Edelmaier, Oliver Sweezy-Schindler, Adam Lamson, Zachary Gergely, Eileen O’Toole, Ammon Crapo, Loren Hough, J. Richard McIntosh ...
FAK transduces extracellular forces that orient the mitotic spindle and control tissue morphogenesis
Spindle orientation is critical for proper morphogenesis of organs and tissues as well as for the maintenance of tissue morphology. Although significant progress has been made in understanding the ...
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