The coronavirus disease 2019 (COVID-19) pandemic has ravaged the globe for more than a year, with an increasing emergence of new variants of concern that stand to undermine current measures aimed at ...

A recent study published in PLOS Computational Biology designed immunogens to induce antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants. Study: Design of ...

In this example of UShER results, displayed using Nextstrain, sequences representing a hypothetical outbreak are yellow, previously sampled sequences are blue, and branches are labeled by nucleotide ...

The scientists at deCODE Genetics, a subsidiary of Amgen, sought to deepen the understanding of cis-acting influences of sequence variants on CpG methylation. In the study, the scientists were able to ...

Using STING-seq, short for systematic targeting and inhibition of noncoding GWAS loci with single cell sequencing, Sanjana and his team identified promising sequence variants linked to various ...

Structural variations (SVs), including insertions, deletions, inversions, and substitutions, can profoundly influence gene ...