Hypertrophic chondrocytes are deeply involved in the growth of mammalian bones. Researchers find that these cells transform into multiple functional cell types, including those responsible for ...

Osteoblasts derived from MSCs are cells required for bone formation. Oxidative phosphorylation produces a lot of ATP and other products including NAD+ and ROS. These factors play important roles in ...

The discovery of a family with sequence similarity 102 member A (Fam102a) protein as a novel bone remodeling factor that regulates both osteoclast and osteoblast differentiation can aid the ...

An international collaboration study reveals how evolution and locomotion patterns, such as bipedalism, shaped bone ...

Am J Health Syst Pharm. 2006;63(5):419-430. During resorption, growth factors and proteins released from osteoblast precursors and bone stimulate the differentiation, chemotaxis, and proliferation of ...

Bones are the living tissue on which the human skeleton is constructed and play a key role in enabling physical movements. The structural integrity of bones has been attributed to bone remodeling-aa ...

For those suffering from primary bone cancer — which is cancer that originates in the bones — a promising new medication may be on the horizon. The drug, called CADD522, works by blocking a gene ...