Potassium channels can become nonconducting via inactivation at a gate inside the highly conserved selectivity filter (SF) region near the extracellular side of the membrane. In certain ligand-gated ...

Intrigued by the properties of ion channel proteins commonly observed in cells, researchers have developed the first synthetic mechanosensitive potassium channel using a newly developed aromatic ...

Scientists applied molecular dynamics simulations to visualize how potassium ions pass through a potassium ion channel at atomic resolution for the first time. (Nanowerk News) The patch clamp ...

The cell membranes of all organisms contain ion channels that permit ions to pass into or out of the cell, and these channels play extremely important roles in fundamental physiological processes such ...

Following this design principle, the researchers create angstrom-scale pores in bi-layer graphene sheets, and decorate the two pore edges with twisted rings of carbonyl groups. The artificial ion ...

Ion selectivity is an important property of cell membrane ion channels. For example, potassium ion channels are more permeable to potassium ions than to sodium ions. The mechanism underlying the ready ...

Larger K+ (ionic radius: 1.3 Å) can selectively permeate larger Na + (ionic radius: 1.0 Å) through biological potassium ion channels, with selectivity ratios greater than 1000-fold. Scientists have ...

Walter and Eliza Hall Institute scientists have made a significant advance in understanding how potassium channels, which permit the flow of electric currents central to many of the body's biological ...

Biological potassium ion channels allow selective permeation of larger K+ (ionic radius of 1.3 Å) over smaller Na+ (1.0 Å) with selectivity ratio over 1,000-fold. For decades, scientists have long ...