Perforated necrotizing enterocolitis is a major cause of morbidity and mortality in premature infants, and the optimal treatment is uncertain. We designed this multicenter randomized trial to compare ...

Machine learning enabled researchers to identify a genetic biomarker for predicting perforated appendicitis in children presenting with suspected appendicitis, according to a single-center prospective ...

For children with a perforated appendix, early appendectomy appears to reduce the time away from normal activities and has fewer adverse events as compared to another common option, the interval ...

Patients presenting with non-specific abdominal pain concerning for acute appendicitis are common in Emergency Departments. It has traditionally been taught that, untreated, appendicitis will progress ...

Appendicitis is a condition in which the appendix, a finger-shaped pouch that opens into the large intestine, becomes swollen and filled with pus. Appendicitis can be caused by a bacterial infection ...

Antibiotic management of acute uncomplicated appendicitis among children was inferior to appendectomy, a randomized non-inferiority trial showed. For nearly 850 children with available primary outcome ...

Appendicitis symptoms start with belly pain that moves and intensifies in your lower right side. Without surgery, perforated appendicitis can lead to serious complications like peritonitis or sepsis.

Antibiotic treatment while awaiting appendectomy does not lower risk for appendiceal perforation in patients with uncomplicated acute appendicitis, according to a new study. While the percentage of ...