The tricarboxylic acid cycle: Oxidation in the round

Having considered localization of respiratory functions in mitochondria and in prokaryotic cells, it's time to return to the ...
JSTOR Daily

Genetic activation of pyruvate dehydrogenase alters oxidative substrate selection to induce skeletal muscle insulin resistance

Yasmeen Rahimi, João-Paulo G. Camporez, Max C. Petersen, Dominik Pesta, Rachel J. Perry, Michael J. Jurczak, Gary W. Cline, Gerald I. Shulman Proceedings of the National Academy of Sciences of the ...
Nature

Nutrient Utilization in Humans: Metabolism Pathways

Energy is trapped in the chemical bonds of nutrient molecules. How is it then made usable for cellular functions and biosynthetic processes? Aa Aa Aa Where does the energy that makes life possible ...
GEN

Structure of Mitochondrial Pyruvate Carrier Drug Target Bound to Inhibitors Revealed

Scientists led by a team at the Medical Research Council (MRC) Mitochondrial Biology Unit, University of Cambridge, have worked out how a molecular machine found in mitochondria—the “powerhouses” of ...