Osteogenesis imperfecta (OI) refers to a group of rare genetic bone disorders that results in the formation of fragile bones. In patients with OI, the matrix that makes up the bone has been found to ...

The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...

"[...] our work suggests that increased mtROS or decreased Atg7-dependent autophagy in osteoblastic cells, as well as reduced osteocyte dendrite number – common ...

Furthermore, the number of osteocyte dendrites-elongated structures that help in regulation of bone remodeling-was reduced in the mutant mice. Additional genomic analysis of cells obtained from the ...

Researchers develop a genetically modified mouse model to uncover the links between dendrite defects in osteocytes and impaired bone remodeling CHINA, August 12, 2025 ...