Antisera were raised to the 210,000-dalton and the 49,000-dalton proteins of a fraction enriched in intermediate (10 nm) filaments from human brain. Proteins of the filament preparation were separated ...

Just as the skeleton and muscles move the human body and hold its shape, the cells of the body are stabilized and moved by a cellular skeleton. This cellular skeleton is a dynamic structure, ...

Living cells are constantly exposed to a wide variety of mechanical stresses: heart and lungs must withstand expansion and contraction; our skin must be resistant to tearing whilst retaining ...

The cytoplasm of eukaryotic cells contains an elaborate filamentous protein meshwork — the cytoskeleton — which comprises three distinct but integrated fibrous polymers: filamentous actin (F-actin; ...

This is a preview. Log in through your library . Abstract The classification of MAP 2 as a microtubule-associated protein is based on its affinity for microtubules in vitro and its filamentous ...

Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an estrogen independent manner. Targeting vimentin and/or the long ...

Glial Fibrillary Acidic Protein (GFAP) is a class-III intermediate filament that is mostly produced in astrocytic glial cells in the central nervous system. Astrocytes have important functions in ...