As Alzheimer’s disease pathology advances, tangles propagate throughout the brain in a fairly stereotypical pattern. Yet tau PET scans of people at the same disease stage are not identical. Could ...

A novel mathematical approach enables the identification of brain regions whose connectivity shifts in autism or aging, informing targeted brain stimulation therapies.

It is a central question in neuroscience to understand how different regions of the brain interact, how strongly they "talk" ...

Upper panel displays functional MRI (fMRI) maps obtained from the functional connectivity multivariate patterns analysis conducted on dataset 1 and dataset 2. In particular, the average connectivity ...

In a paper titled, "Multimodal MRI reveals brainstem connections that sustain wakefulness in human consciousness," published today in Science Translational Medicine, a group of researchers at ...

The brain is never completely at rest. Even without external input, it produces spontaneous neural activity that creates synchronized fluctuations across different regions - a process known as ...

A new study involved high-resolution scans that enabled the researchers to visualize brain connections at submillimeter spatial resolution. Together, these pathways form a 'default ascending arousal ...

This functional connectivity map, a kind of “fingerprint” of the brain, displays how different regions interact with each other in 12-year-olds. The map was constructed from resting-state MRIs, where ...

Human consciousness requires arousal (i.e., wakefulness) and awareness Brain imaging studies over the last decade have produced connectivity maps of the cortical networks that sustain awareness, but ...