Bacteriophage PRD1 shares many structural and functional similarities with adenovirus. A major difference is the PRD1 internal membrane, which acts in concert with vertex proteins to translocate the ...

Assembly and budding of a virus from a membrane microdomain. Viruses have an outer protein shell called a capsid which surrounds the viral nucleic acid. Enveloped viruses, such as HIV, have an ...

Though treatments are available, there is no cure or vaccine from HIV, which impacts about 38 million people worldwide. It's difficult to target the RNA genome of the HIV virus in part because it ...

For the first time, scientists know what happens to a virus’ shape when it invades a host cell, thanks to a new experiment. Understanding how the virus shape specifically changes could lead to more ...

Scientists at the Electron Bio-Imaging Centre (eBIC) at Diamond Light Source, in the U.K., have harnessed a new technique, using cryo-electron tomography (cryoET) and subtomogram averaging (STA) to ...

Herpes simplex virus type 1 (HSV-1) interacts with the trafficking pathway of the host cell to acquire its viral envelope, but which cellular compartment this membrane derives from has been ...