A single enzyme that can generate all four nucleoside triphosphates, the building blocks of ribonucleic acid (RNA), has been ...
DNA synthesis is vital to several processes in biopharmaceutical innovation, including the development of gene therapies, CRISPR gene editing, antisense oligonucleotides and RNA therapies. The need ...
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Single enzyme enables low-cost synthesis of all RNA nucleotides
A single enzyme that can generate all four nucleotide triphosphates, the building blocks of ribonucleic acid (RNA), was ...
A new technology elucidated yesterday in the journal Nature has the potential to be a leap forward in DNA synthesis, allowing ...
This diagram depicts the chemical structure of pyrimidine, a six-membered aromatic ring with two nitrogen atoms at positions 1 and 3 (highlighted in blue). The remaining positions are occupied by ...
DNA is the raw material of modern medicine yet is the only part of drug development not accessible at the lab bench. DNA synthesis, the first step in most biological workflows including gene synthesis ...
While the COVID-19 vaccines introduced many people to RNA-based medicines, RNA oligonucleotides have already been on the market for years to treat diseases like Duchenne Muscular Dystrophy and ...
A new paper published in Nature Biotechnology this week titled, “Template-independent enzymatic synthesis of RNA oligonucleotides,” provides details of a method for synthesizing single-stranded RNA ...
Researchers say discoveries could expand the CRISPR toolbox and lead to more efficient, rapid diagnostic tools for detecting COVID-19, influenza, and RSV.
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