The coagulation cascade is a finely balanced system essential for maintaining haemostasis, yet its disruption can lead to either a propensity for bleeding or an increased risk of clot formation.

Studies by researchers at Columbia University Irving Medical Center suggest that one of the immune system’s oldest branches, the complement system, and coagulation dysfunction, may be influencing the ...

Coagulation disorders refer to conditions that affect how the body controls blood clotting. This can mean the body forms too many or too few blood clots. Coagulation disorders are usually due to a ...

Hemostasis is a complex system composed of many procoagulant and regulatory pathways. Multiple pathways, such as the intrinsic pathway, platelet activation and the tissue factor pathway, can affect ...

Hemophilia A and B involve deficiencies in coagulation factors VIII and IX, with traditional treatments requiring frequent infusions. Nonfactor therapies, including Hemlibra and rebalancing agents, ...

Blood clotting can lead to life-threatening heart attacks and strokes, and current treatments can lead to excessive bleeding and other worrisome side effects. But researchers now say they've found a ...

A novel class of antithrombotic medication, the factor XIa inhibitors, has had a rocky start but is powering through phase III trials, which are now underway. MedPage Today sat down to discuss the ...

February 6, 2007 (Seattle, WA) - Variants in key coagulation and anticoagulation proteins were more common in postmenopausal women who developed venous thrombosis (VT) than in those who did not, ...

As people age they become more prone to blood clotting diseases, which can be caused when blood platelets clump together. This clumping can lead to strokes and cardiovascular disease. For decades, ...

UK Biobank analysis found cancer diagnosis raised cardiovascular disease mortality by 50%, with proteomic signals in ...

Pathway to Cures, the venture philanthropy fund of the National Bleeding Disorders Foundation (NBDF), is pleased to announce its investment in SeraGene Therapeutics, a pioneering biotechnology company ...