Successfully producing large quantities of biotherapeutics, including monoclonal antibodies and recombinant protein products, depends on robust and reliable cell line development (CLD). Issues that ...

There are hundreds of cell types in the human body, each with a specific role spelled out in their DNA. In theory, all it ...

Insect cell lines have emerged as critical platforms for the production of recombinant proteins, vaccines and other biopharmaceuticals. Their ability to perform post‐translational modifications and to ...

To date, more than 100 clinical trials with human pluripotent stem cell (hPSC)-derived products have been initiated worldwide and an increasing number of potential hPSC-derived clinical products have ...

A 'pocket' on the protein cyclin B is responsible for ensuring that the steps of cell division take place in the correct order. Cell division is key for life. Every organism -- from the smallest yeast ...

How do you currently identify and select cells for further growth, characterization and processing? Many available cell-selection technologies lack the sensitivity necessary to preserve cell health ...

If reproducible results are considered the cornerstone of science, then one must also consider the Replication Crisis to be the anathema of experimentation. A PLOS study in 2015 concluded that at ...