Cancer cells carry thousands of mutations, but not all mutations are created equal. Some make tumors highly visible to the ...

Scientists have created a complete map showing how hundreds of possible mutations in a key cancer gene influence tumor growth ...

Study results indicate that mutation strength may shape both tumor–immune system interactions and immunotherapy response.

Mapping diverse mutations within a cancer hotspot revealed that distinct variants drive tumor growth to different extents, which could guide anticancer therapies.

One of the most important developments in breast cancer, especially for people with hormone receptor-positive (HR+) advanced ...

Scientists have created a complete map showing how hundreds of possible mutations in a key cancer gene influence tumor growth. The study focused on CTNNB1, a gene that produces the protein β-catenin, ...

Scientists have created a complete map showing how hundreds of possible mutations in a key cancer gene influence tumour growth.

Researchers have found that women who are diagnosed with breast cancer before the age of 55 and carry an inherited mutation in the breast cancer susceptibility genes BRCA1 or BRCA2 ...

A study led by Aaron Hobbs, Ph.D., and Rachel Burge, Ph.D., at MUSC Hollings Cancer Center, reveals why a specific gene mutation behaves differently from other variants.

A CRISPR system detects rare cancer mutations in blood with single-nucleotide precision, outperforming ddPCR through engineered RNA guides and isothermal amplification. (Nanowerk Spotlight) Hidden ...

Hereditary breast cancer results from inherited mutations, primarily in BRCA1 and BRCA2, increasing lifetime cancer risk. Additional genes like TP53, PTEN, PALB2, CHEK2, and ATM also contribute to ...

Some 17 million Americans are living with genetic mutations tied to an increased risk of getting cancer, Cleveland Clinic researchers warned Monday. And the more than 3,400 mutations identified – ...